Cosmetic · Lot AP-24-G0220
C14H24CuN6O4 · 403.9 Da · CAS 49557-75-7
Copper-bound tripeptide. Studied for skin remodeling, collagen synthesis, and antioxidant pathways.
01 · Overview
GHK-Cu is the copper(II) complex of the naturally occurring tripeptide Gly-His-Lys, first isolated from human plasma in 1973. Plasma concentrations decline substantially with age — from ~200 ng/mL at age 20 to ~80 ng/mL by 60.
Research literature has extensively characterized its effects on skin remodeling, collagen synthesis, fibroblast migration, and gene-expression patterns related to wound healing. The copper redox activity is silenced when the ion is complexed with GHK, which allows non-toxic copper delivery into cells. Widely used under INCI name 'Copper tripeptide-1' in cosmetic research.
02 · Handling
Excursion above 25 °C for more than 48 h: request replacement.
Reconstitution protocols vary by compound and study. Your per-lot certificate lists the solvent used during purity verification.
Need a specific protocol? The research liaison team can provide compound-specific guidance on request.
03 · Specifications
| Compound | GHK-Cu |
|---|---|
| CAS | 49557-75-7 |
| Molecular formula | C14H24CuN6O4 |
| Molecular weight | 403.9 Da |
| Salt form | Copper(II) complex |
| Purity (RP-HPLC 220 nm) | ≥ 99.0% (lot: 99.61%) |
| Fill | 50 mg · lyophilized |
| Appearance | White lyophilized cake |
| Storage | −20 °C, light-protected, desiccated |
04 · Certificate of analysis
The lot-specific COA is bound to the identifier printed on your vial. Scan the QR code, or download the current release.
Access
Researchers apply once; repeat orders are routed through your existing account. Pricing on request.
Request access →